Research Projects

Hodgkin Lymphoma in SA Children Adolescents from 2000-2010

Hodgkin Lymphoma in SA Children Adolescents from 2000-2010

Dr Jennifer Geel

Dr Jennifer Geel

Dr Jennifer Geel

Title of the project

Hodgkin Lymphoma in South African Children Adolescents from 2000-2010: A first report by the South African Children’s Cancer Study Group.

Project Description

The purpose of this research is to see how many children in South Africa develop Hodgkin lymphoma, and how many of these children survive.

We aim to determine which factors impact on survival in these children. The parameters that will be examined include: age, sex, race, stage at diagnosis, HIV status and treatment protocol.

The South African Children’s Cancer Study Group will consider the results of the study and make recommendations for its member units in terms of improvements, with the aim of increasing survival rates of children with Hodgkin Lymphoma in South Africa. We intend to bring HL survival rates closer to the higher survival rates shown in other countries. We would like to establish guidelines for the ideal treatment for Hodgkin Lymphoma in a South African setting. The aims of this study coincide with those of the SACCSG, namely to increase early detection of childhood cancer and optimise management. In high income countries it has become standard to do a PET – CT to decide what stage disease a patient has and how they have responded after 2 cycles of treatment and PET – CT currently costs between R20000 to R30000 and is unavailable in certain centres. A treatment regimen has been agreed upon: it consists of chemotherapy which is available in all South African centres, and can be given on an out-patient basis and has relatively few side effects.

The project has already improved the standard of care of children and adolescents with HL in our centres (Charlotte Maxeke Johannesburg Academic Hospital and Wits Donald Gordon Medical Centre) and I hope that the same effect is achieved in the other centres around South Africa.


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