Prof Sinead Delany-Moretlwe – Factors associated with anogenital HPV infection and disease prevalence, incidence, persistence: a prospective cohort study
Prof Sinead Delany-Moretlwe
- Director: Research, Wits Reproductive and HIV Institute (Wits RHI).
Associate Professor, University of the Witwatersrand, Wits, School of Clinical Medicine, Faculty of Health Sciences
Title of the project
Factors associated with anogenital HPV infection and disease prevalence, incidence, persistence: a prospective cohort study.
In an established cohort of 300 HIV positive men, of whom two thirds are currently on ART, we plan to extend follow up in these men from 12 to 24 months in order to assess factors that are associated with the incidence, persistence and progression of anogenital HPV infection and associated anal lesions. In addition, we aim to evaluate the association between HPV 16/18 genital viral loads in predicting anal cytological abnormality and progression of disease. With this application we request support for testing of 18 and 24 months samples for HPV DNA genotypes and HPV 16/18 viral load, anal cytology collected from this cohort.